mouse BCL2 Over-expression AAV

Cat. No: AAV-253879

Availability: 3-5 weeks

Name: AAV-m-BCL2

This is an AAV expressing Mouse Bcl2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Bcl2
Gene Name: B cell leukemia/lymphoma 2
Gene ID: 12043
Gene Synonyms: AW986256; Bcl-2; C430015F12Rik; D630044D05Rik; D830018M01Rik
ORF Size: 711 bp
RefSeq#: BC095964
Gene Description: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
UniGene ID: Mm.477249