mouse BAD Over-expression AAV

Cat. No: AAV-253590

Availability: 3-5 weeks

Name: AAV-m-BAD

This is an AAV expressing Mouse Bad.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Bad
Gene Name: BCL2-associated agonist of cell death
Gene ID: 12015
Gene Synonyms: AI325008; Bbc2
ORF Size: 615 bp
RefSeq#: BC006762
Gene Description: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
UniGene ID: Mm.4387