mouse ACO1 Over-expression AAV

Cat. No: AAV-251916

Availability: 3-5 weeks

Name: AAV-m-ACO1

This is an AAV expressing Mouse Aco1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Aco1
Gene Name: aconitase 1
Gene ID: 11428
Gene Synonyms: Aco-1; Irebp; Irp1
ORF Size: 2670 bp
RefSeq#: BC005454
Gene Description: Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding|Function: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity).
UniGene ID: Mm.331547