mouse ABCE1 Over-expression AAV

Cat. No: AAV-251799

Availability: 3-5 weeks

Name: AAV-m-ABCE1

This is an AAV expressing Mouse Abce1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Abce1
Gene Name: ATP-binding cassette, sub-family E (OABP), member 1
Gene ID: 24015
Gene Synonyms: C79080; Oabp; RLI; Rnaseli; RNS41
ORF Size: 1800 bp
RefSeq#: BC005422
Gene Description: Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
UniGene ID: Mm.5831