mouse RUNX1 Over-expression AAV

Cat. No: AAV-250906

Availability: 3-5 weeks

Name: AAV-m-RUNX1

This is an AAV expressing Mouse Runx1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Runx1
Gene Name: runt related transcription factor 1
Gene ID: 12394
Gene Synonyms: AML1; CBF-alpha-2; Cbfa2; Pebp2a2; Pebpa2b
ORF Size: 1320 bp
RefSeq#: BC069929
Gene Description: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation.
UniGene ID: Mm.4081