mouse 1600027N09RIK Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-250238
Availability:
3-5 weeks
Name:
AAV-m-1600027N09RIK
This is an AAV expressing Mouse Mrgbp.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Mrgbp
- Gene Name
- MRG/MORF4L binding protein
- Gene ID
- 73247
- Gene Synonyms
- 1600027N09Rik; AW060503; C80444
- ORF Size
- 615 bp
- RefSeq#
- BC116734
- Gene Description
- Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
- UniGene ID
- Mm.426558
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