mouse 1110008J03RIK Over-expression AAV

Cat. No: AAV-250115

Availability: 3-5 weeks

Name: AAV-m-1110008J03RIK

This is an AAV expressing Mouse Rita1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Rita1
Gene Name: RBPJ interacting and tubulin associated 1
Gene ID: 100764
Gene Synonyms: 1110008J03Rik; AI853657; C86297; Rita
ORF Size: 762 bp
RefSeq#: BC021365
Gene Description: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
UniGene ID: Mm.9654