human WDFY3 Over-expression AAV

Cat. No: AAV-234238

Availability: 3-5 weeks

Name: AAV-h-WDFY3

This is an AAV expressing Human WDFY3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: WDFY3
Gene Name: WD repeat and FYVE domain containing 3
Gene ID: 23001
Gene Synonyms: ALFY; ZFYVE25
ORF Size: 1315 bp
RefSeq#: BC015214
Gene Description: WDFY3 encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.
HGNC ID: HGNC:20751