human OSTM1 Over-expression AAV

Cat. No: AAV-230014

Availability: 3-5 weeks

Name: AAV-h-OSTM1

This is an AAV expressing Human OSTM1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: OSTM1
Gene Name: osteopetrosis associated transmembrane protein 1
Gene ID: 28962
Gene Synonyms: GIPN; GL; HSPC019; OPTB5
ORF Size: 1005 bp
RefSeq#: BC068581
Gene Description: OSTM1 encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
UniGene ID: Hs.719130
HGNC ID: HGNC:21652