human ASCL1 Over-expression AAV

Cat. No: AAV-229295

Availability: 3-5 weeks

Name: AAV-h-ASCL1

This is an AAV expressing Human ASCL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ASCL1
Gene Name: achaete-scute family bHLH transcription factor 1
Gene ID: 429
Gene Synonyms: ASH1; bHLHa46; HASH1; MASH1
ORF Size: 711 bp
RefSeq#: BC031299
Gene Description: ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
UniGene ID: Hs.704281
HGNC ID: HGNC:738