human IL23A Over-expression AAV

Cat. No: AAV-229103

Availability: 3-5 weeks

Name: AAV-h-IL23A

This is an AAV expressing Human IL23A.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: IL23A
Gene Name: interleukin 23 subunit alpha
Gene ID: 51561
Gene Synonyms: IL-23; IL-23A; IL23P19; P19; SGRF
ORF Size: 570 bp
RefSeq#: BC066269
Gene Description: IL23A encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
UniGene ID: Hs.98309
HGNC ID: HGNC:15488