human ZIC2 Over-expression AAV

Cat. No: AAV-228253

Availability: 3-5 weeks

Name: AAV-h-ZIC2

This is an AAV expressing Human ZIC2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ZIC2
Gene Name: Zic family member 2
Gene ID: 7546
Gene Synonyms: HPE5
ORF Size: 1596 bp
RefSeq#: BC172274
Gene Description: ZIC2 encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. ZIC2 is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
UniGene ID: Hs.653700
HGNC ID: HGNC:12873