human YME1L1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227979
Availability:
3-5 weeks
Name:
AAV-h-YME1L1
This is an AAV expressing Human YME1L1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- YME1L1
- Gene Name
- YME1 like 1 ATPase
- Gene ID
- 10730
- Gene Synonyms
- FTSH; MEG4; PAMP; YME1L
- ORF Size
- 2151 bp
- RefSeq#
- BC023507
- Gene Description
- YME1L1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.499145
- HGNC ID
- HGNC:12843
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