human XCR1 Over-expression AAV

Cat. No: AAV-227876

Availability: 3-5 weeks

Name: AAV-h-XCR1

This is an AAV expressing Human XCR1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: XCR1
Gene Name: X-C motif chemokine receptor 1
Gene ID: 2829
Gene Synonyms: CCXCR1; GPR5
ORF Size: 1002 bp
RefSeq#: BC069589
Gene Description: XCR1 is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.248116
HGNC ID: HGNC:1625