human VEGFC Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227459
Availability:
3-5 weeks
Name:
AAV-h-VEGFC
This is an AAV expressing Human VEGFC.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- VEGFC
- Gene Name
- vascular endothelial growth factor C
- Gene ID
- 7424
- Gene Synonyms
- Flt4-L; LMPH1D; VRP
- ORF Size
- 1260 bp
- RefSeq#
- BC063685
- Gene Description
- VEGFC is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.
- UniGene ID
- Hs.435215
- HGNC ID
- HGNC:12682
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