human UNC119 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-227180
Availability:
3-5 weeks
Name:
AAV-h-UNC119
This is an AAV expressing Human UNC119.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- UNC119
- Gene Name
- unc-119 lipid binding chaperone
- Gene ID
- 9094
- Gene Synonyms
- HRG4; IMD13; POC7; POC7A
- ORF Size
- 723 bp
- RefSeq#
- BC027176
- Gene Description
- UNC119 is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene.
- UniGene ID
- Hs.410455
- HGNC ID
- HGNC:12565
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