human TNFSF4 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-226112
Availability:
3-5 weeks
Name:
AAV-h-TNFSF4
This is an AAV expressing Human TNFSF4.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TNFSF4
- Gene Name
- tumor necrosis factor superfamily member 4
- Gene ID
- 7292
- Gene Synonyms
- CD134L; CD252; GP34; OX-40L; OX4OL; TNLG2B; TXGP1
- ORF Size
- 402 bp
- RefSeq#
- BC041663
- Gene Description
- TNFSF4 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
- UniGene ID
- Hs.181097
- HGNC ID
- HGNC:11934
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