human TINAG Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-225535
Availability:
3-5 weeks
Name:
AAV-h-TINAG
This is an AAV expressing Human TINAG.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TINAG
- Gene Name
- tubulointerstitial nephritis antigen
- Gene ID
- 27283
- Gene Synonyms
- TIN-AG
- ORF Size
- 1431 bp
- RefSeq#
- BC070278
- Gene Description
- TINAG encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and temporal pattern throughout nephrogenesis.
- UniGene ID
- Hs.127011
- HGNC ID
- HGNC:14599
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