human TAX1BP1 Over-expression AAV

Cat. No: AAV-225050

Availability: 3-5 weeks

Name: AAV-h-TAX1BP1

This is an AAV expressing Human TAX1BP1.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TAX1BP1
Gene Name: Tax1 binding protein 1
Gene ID: 8887
Gene Synonyms: CALCOCO3; T6BP; TXBP151
ORF Size: 2370 bp
RefSeq#: BC050358
Gene Description: TAX1BP1 encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.34576
HGNC ID: HGNC:11575