human TARBP2 Over-expression AAV

Cat. No: AAV-224972

Availability: 3-5 weeks

Name: AAV-h-TARBP2

This is an AAV expressing Human TARBP2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TARBP2
Gene Name: TARBP2, RISC loading complex RNA binding subunit
Gene ID: 6895
Gene Synonyms: LOQS; TRBP; TRBP1; TRBP2
ORF Size: 1101 bp
RefSeq#: BC005860
Gene Description: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.
UniGene ID: Hs.326
HGNC ID: HGNC:11569