human TAPT1 Over-expression AAV

Cat. No: AAV-224970

Availability: 3-5 weeks

Name: AAV-h-TAPT1

This is an AAV expressing Human TAPT1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TAPT1
Gene Name: transmembrane anterior posterior transformation 1
Gene ID: 202018
Gene Synonyms: CMVFR; OCLSBG
ORF Size: 1704 bp
RefSeq#: BC066899
Gene Description: TAPT1 encodes a highly conserved, putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. TAPT1 is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant encoding a substantially different isoform has been described, but its biological validity has not been determined.
UniGene ID: Hs.479223
HGNC ID: HGNC:26887