human SYT14 Over-expression AAV

Cat. No: AAV-224845

Availability: 3-5 weeks

Name: AAV-h-SYT14

This is an AAV expressing Human SYT14.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SYT14
Gene Name: synaptotagmin 14
Gene ID: 255928
Gene Synonyms: SCAR11; sytXIV
ORF Size: 1809 bp
RefSeq#: BC130323
Gene Description: SYT14 is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate membrane trafficking in synaptic transmission. The encoded protein is a calcium-independent synaptotagmin. Mutations in this gene are a cause of autosomal recessive spinocerebellar ataxia-11 (SCAR11), and a t(1;3) translocation of this gene has been associated with neurodevelopmental abnormalities. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 4.
UniGene ID: Hs.658866
HGNC ID: HGNC:23143