human STAMBP Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-224506
Availability:
3-5 weeks
Name:
AAV-h-STAMBP
This is an AAV expressing Human STAMBP.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- STAMBP
- Gene Name
- STAM binding protein
- Gene ID
- 10617
- Gene Synonyms
- AMSH; MICCAP
- ORF Size
- 1275 bp
- RefSeq#
- BC007682
- Gene Description
- Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
- UniGene ID
- Hs.657598
- HGNC ID
- HGNC:16950
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