human STAM2 Over-expression AAV

Cat. No: AAV-224505

Availability: 3-5 weeks

Name: AAV-h-STAM2

This is an AAV expressing Human STAM2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: STAM2
Gene Name: signal transducing adaptor molecule 2
Gene ID: 10254
Gene Synonyms: Hbp; STAM2A; STAM2B
ORF Size: 1578 bp
RefSeq#: BC028740
Gene Description: STAM2 is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
UniGene ID: Hs.17200
HGNC ID: HGNC:11358