human SPRY4 Over-expression AAV

Cat. No: AAV-224275

Availability: 3-5 weeks

Name: AAV-h-SPRY4

This is an AAV expressing Human SPRY4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SPRY4
Gene Name: sprouty RTK signaling antagonist 4
Gene ID: 81848
Gene Synonyms: HH17
ORF Size: 900 bp
RefSeq#: BC125096
Gene Description: SPRY4 is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway. It is positioned upstream of RAS (see HRAS; MIM 190020) activation and impairs the formation of active GTP-RAS (Leeksma et al., 2002 (PubMed 12027893)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.323308
HGNC ID: HGNC:15533