human SPINT2 Over-expression AAV

Cat. No: AAV-224201

Availability: 3-5 weeks

Name: AAV-h-SPINT2

This is an AAV expressing Human SPINT2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SPINT2
Gene Name: serine peptidase inhibitor, Kunitz type 2
Gene ID: 10653
Gene Synonyms: DIAR3; HAI-2; HAI2; Kop; PB
ORF Size: 759 bp
RefSeq#: BC011955
Gene Description: SPINT2 encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. SPINT2 is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.31439
HGNC ID: HGNC:11247