human SP100 Over-expression AAV

Cat. No: AAV-224036

Availability: 3-5 weeks

Name: AAV-h-SP100

This is an AAV expressing Human SP100.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SP100
Gene Name: SP100 nuclear antigen
Gene ID: 6672
Gene Synonyms: lysp100b
ORF Size: 1443 bp
RefSeq#: BC011562
Gene Description: SP100 encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.
UniGene ID: Hs.369056
HGNC ID: HGNC:11206