human SMOC2 Over-expression AAV

Cat. No: AAV-223764

Availability: 3-5 weeks

Name: AAV-h-SMOC2

This is an AAV expressing Human SMOC2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SMOC2
Gene Name: SPARC related modular calcium binding 2
Gene ID: 64094
Gene Synonyms: bA270C4A.1; bA37D8.1; dJ421D16.1; DTDP1; MST117; MSTP117; MSTP140; SMAP2
ORF Size: 1341 bp
RefSeq#: BC028420
Gene Description: SMOC2 encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.487200
HGNC ID: HGNC:20323