human SMARCE1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-223729
Availability:
3-5 weeks
Name:
AAV-h-SMARCE1
This is an AAV expressing Human SMARCE1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SMARCE1
- Gene Name
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
- Gene ID
- 6605
- Gene Synonyms
- BAF57; CSS5
- ORF Size
- 1236 bp
- RefSeq#
- BC011017
- Gene Description
- SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.
- UniGene ID
- Hs.696086
- HGNC ID
- HGNC:11109
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