human SLC6A5 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-223571
Availability:
3-5 weeks
Name:
AAV-h-SLC6A5
This is an AAV expressing Human SLC6A5.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SLC6A5
- Gene Name
- solute carrier family 6 member 5
- Gene ID
- 9152
- Gene Synonyms
- GLYT-2; GLYT2; HKPX3; NET1
- ORF Size
- 2394 bp
- RefSeq#
- BC096319
- Gene Description
- SLC6A5 encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea.
- UniGene ID
- Hs.136557
- HGNC ID
- HGNC:11051
Related Products
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