human SLC27A2 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-223312
Availability:
3-5 weeks
Name:
AAV-h-SLC27A2
This is an AAV expressing Human SLC27A2.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SLC27A2
- Gene Name
- solute carrier family 27 member 2
- Gene ID
- 11001
- Gene Synonyms
- ACSVL1; FACVL1; FATP2; hFACVL1; HsT17226; VLACS; VLCS
- ORF Size
- 1704 bp
- RefSeq#
- BC057770
- Gene Description
- SLC27A2 is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.11729
- HGNC ID
- HGNC:10996
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