human SH2B3 Over-expression AAV

Cat. No: AAV-222878

Availability: 3-5 weeks

Name: AAV-h-SH2B3

This is an AAV expressing Human SH2B3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SH2B3
Gene Name: SH2B adaptor protein 3
Gene ID: 10019
Gene Synonyms: IDDM20; LNK
ORF Size: 1728 bp
RefSeq#: BC136451
Gene Description: SH2B3 encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
UniGene ID: Hs.506784
HGNC ID: HGNC:29605