human SCYL1 Over-expression AAV

Cat. No: AAV-222406

Availability: 3-5 weeks

Name: AAV-h-SCYL1

This is an AAV expressing Human SCYL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SCYL1
Gene Name: SCY1 like pseudokinase 1
Gene ID: 57410
Gene Synonyms: GKLP; HT019; NKTL; NTKL; P105; SCAR21; TAPK; TEIF; TRAP
ORF Size: 2427 bp
RefSeq#: BC069233
Gene Description: SCYL1 encodes a transcriptional regulator belonging to the SCY1-like family of kinase-like proteins. The protein has a divergent N-terminal kinase domain that is thought to be catalytically inactive, and can bind specific DNA sequences through its C-terminal domain. It activates transcription of the telomerase reverse transcriptase and DNA polymerase beta genes. The protein has been localized to the nucleus, and also to the cytoplasm and centrosomes during mitosis. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.238839
HGNC ID: HGNC:14372