human SCAP Over-expression AAV

Cat. No: AAV-222307

Availability: 3-5 weeks

Name: AAV-h-SCAP

This is an AAV expressing Human SCAP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SCAP
Gene Name: SREBF chaperone
Gene ID: 22937
ORF Size: 2718 bp
RefSeq#: BC020987
Gene Description: SCAP encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
UniGene ID: Hs.531789
HGNC ID: HGNC:30634