human SAT1 Over-expression AAV

Cat. No: AAV-222268

Availability: 3-5 weeks

Name: AAV-h-SAT1

This is an AAV expressing Human SAT1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SAT1
Gene Name: spermidine/spermine N1-acetyltransferase 1
Gene ID: 6303
Gene Synonyms: DC21; KFSD; KFSDX; SAT; SSAT; SSAT-1
ORF Size: 516 bp
RefSeq#: BC002503
Gene Description: SAT1 belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.
UniGene ID: Hs.28491
HGNC ID: HGNC:10540