human SAR1B Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-222250
Availability:
3-5 weeks
Name:
AAV-h-SAR1B
This is an AAV expressing Human SAR1B.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SAR1B
- Gene Name
- secretion associated Ras related GTPase 1B
- Gene ID
- 51128
- Gene Synonyms
- ANDD; CMRD; GTBPB; SARA2
- ORF Size
- 597 bp
- RefSeq#
- BC093034
- Gene Description
- SAR1B is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
- UniGene ID
- Hs.432984
- HGNC ID
- HGNC:10535
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