human RP2 Over-expression AAV

Cat. No: AAV-221521

Availability: 3-5 weeks

Name: AAV-h-RP2

This is an AAV expressing Human RP2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RP2
Gene Name: retinitis pigmentosa 2 (X-linked recessive)
Gene ID: 6102
Gene Synonyms: DELXp11.3; NM23-H10; NME10; TBCCD2; XRP2
ORF Size: 1053 bp
RefSeq#: BC043348
Gene Description: The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death
UniGene ID: Hs.44766
HGNC ID: HGNC:10274