human RLIM Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-221273
Availability:
3-5 weeks
Name:
AAV-h-RLIM
This is an AAV expressing Human RLIM.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RLIM
- Gene Name
- ring finger protein, LIM domain interacting
- Gene ID
- 51132
- Gene Synonyms
- MRX61; NY-REN-43; RNF12
- ORF Size
- 1875 bp
- RefSeq#
- BC013357
- Gene Description
- RLIM is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- UniGene ID
- Hs.653288
- HGNC ID
- HGNC:13429
Related Products
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