human RBL1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-220838
Availability:
3-5 weeks
Name:
AAV-h-RBL1
This is an AAV expressing Human RBL1.
Request a Quote
Please enter your email address and we'll be in touch with more information:
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RBL1
- Gene Name
- RB transcriptional corepressor like 1
- Gene ID
- 5933
- Gene Synonyms
- CP107; p107; PRB1
- ORF Size
- 3045 bp
- RefSeq#
- BC032247
- Gene Description
- RBL1 is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene.
- UniGene ID
- Hs.617220
- HGNC ID
- HGNC:9893
Related Products
Product | Cat No. |
---|---|
AAV-m-RBL1 | AAV-250819 |
Ad-h-RBL1 | ADV-220838 |
Ad-m-RBL1 | ADV-250819 |
AAV-h-RBL1-shRNA | shAAV-220838 |
AAV-m-RBL1-shRNA | shAAV-250819 |
Ad-h-RBL1-shRNA | shADV-220838 |
Ad-m-RBL1-shRNA | shADV-250819 |
Control Products
Vector Biolabs
293 Great Valley Parkway
Malvern, PA 19355
Email: info@vectorbiolabs.com
Phone: +1 484-325-5100
Toll-free (US Only): 877-BIO-LABS
Fax: +1 215-525-1112
Privacy Policy