human RBAK Over-expression AAV

Cat. No: AAV-220822

Availability: 3-5 weeks

Name: AAV-h-RBAK

This is an AAV expressing Human RBAK.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RBAK
Gene Name: RB associated KRAB zinc finger
Gene ID: 57786
Gene Synonyms: ZNF769
ORF Size: 2145 bp
RefSeq#: BC136676
Gene Description: RBAK encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus.
UniGene ID: Hs.396178
HGNC ID: HGNC:17680