human RAPGEF5 Over-expression AAV

Cat. No: AAV-220736

Availability: 3-5 weeks

Name: AAV-h-RAPGEF5

This is an AAV expressing Human RAPGEF5.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RAPGEF5
Gene Name: Rap guanine nucleotide exchange factor 5
Gene ID: 9771
Gene Synonyms: GFR; MR-GEF; REPAC
ORF Size: 1335 bp
RefSeq#: BC039203
Gene Description: Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 (PubMed 10934204)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.713217
HGNC ID: HGNC:16862