human RAD54L Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-220652
Availability:
3-5 weeks
Name:
AAV-h-RAD54L
This is an AAV expressing Human RAD54L.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RAD54L
- Gene Name
- RAD54-like (S. cerevisiae)
- Gene ID
- 8438
- Gene Synonyms
- hHR54; HR54; hRAD54; RAD54A
- ORF Size
- 2244 bp
- RefSeq#
- BC121060
- Gene Description
- RAD54L belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
- UniGene ID
- Hs.642042
- HGNC ID
- HGNC:9826
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