human RAD21 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-220636
Availability:
3-5 weeks
Name:
AAV-h-RAD21
This is an AAV expressing Human RAD21.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RAD21
- Gene Name
- RAD21 cohesin complex component
- Gene ID
- 5885
- Gene Synonyms
- CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1; SCC1
- ORF Size
- 1896 bp
- RefSeq#
- BC050381
- Gene Description
- RAD21 is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
- UniGene ID
- Hs.81848
- HGNC ID
- HGNC:9811
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