human PTGS1 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-220256
Availability:
3-5 weeks
Name:
AAV-h-PTGS1
This is an AAV expressing Human PTGS1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PTGS1
- Gene Name
- prostaglandin-endoperoxide synthase 1
- Gene ID
- 5742
- Gene Synonyms
- COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS
- ORF Size
- 1800 bp
- RefSeq#
- BC029840
- Gene Description
- This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
- UniGene ID
- Hs.201978
- HGNC ID
- HGNC:9604
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