human PPT1 Over-expression AAV

Cat. No: AAV-219694

Availability: 3-5 weeks

Name: AAV-h-PPT1

This is an AAV expressing Human PPT1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PPT1
Gene Name: palmitoyl-protein thioesterase 1
Gene ID: 5538
Gene Synonyms: CLN1; INCL; PPT
ORF Size: 921 bp
RefSeq#: BC008426
Gene Description: PPT1 is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid lipofuscinosis 1 (CLN1, or INCL) and neuronal ceroid lipofuscinosis 4 (CLN4). Two transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.3873
HGNC ID: HGNC:9325