human PPM1G Over-expression AAV

Cat. No: AAV-219582

Availability: 3-5 weeks

Name: AAV-h-PPM1G

This is an AAV expressing Human PPM1G.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PPM1G
Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1G
Gene ID: 5496
Gene Synonyms: PP2CG; PP2CGAMMA; PPP2CG
ORF Size: 1641 bp
RefSeq#: BC022061
Gene Description: PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression.
UniGene ID: Hs.643951
HGNC ID: HGNC:9278