human PPARG Over-expression AAV

Cat. No: AAV-219510

Availability: 3-5 weeks

Name: AAV-h-PPARG

This is an AAV expressing Human PPARG.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PPARG
Gene Name: peroxisome proliferator activated receptor gamma
Gene ID: 5468
Gene Synonyms: CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma
ORF Size: 1434 bp
RefSeq#: BC006811
Gene Description: PPARG encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
UniGene ID: Hs.162646
HGNC ID: HGNC:9236