human POMP Over-expression AAV

Cat. No: AAV-219435

Availability: 3-5 weeks

Name: AAV-h-POMP

This is an AAV expressing Human POMP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: POMP
Gene Name: proteasome maturation protein
Gene ID: 51371
Gene Synonyms: C13orf12; HSPC014; PNAS-110; UMP1
ORF Size: 426 bp
RefSeq#: BC003390
Gene Description: POMP is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.
UniGene ID: Hs.268742
HGNC ID: HGNC:20330