human PNMA3 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-219298
Availability:
3-5 weeks
Name:
AAV-h-PNMA3
This is an AAV expressing Human PNMA3.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PNMA3
- Gene Name
- paraneoplastic Ma antigen 3
- Gene ID
- 29944
- Gene Synonyms
- MA3; MA5
- ORF Size
- 1392 bp
- RefSeq#
- BC105096
- Gene Description
- PNMA3 is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.
- UniGene ID
- Hs.449627
- HGNC ID
- HGNC:18742
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