human PLUNC Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-219242
Availability:
3-5 weeks
Name:
AAV-h-PLUNC
This is an AAV expressing Human BPIFA1.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- BPIFA1
- Gene Name
- BPI fold containing family A member 1
- Gene ID
- 51297
- Gene Synonyms
- bA49G10.5; LUNX; NASG; PLUNC; SPLUNC1; SPURT
- ORF Size
- 771 bp
- RefSeq#
- BC012549
- Gene Description
- BPIFA1 is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.
- UniGene ID
- Hs.211092
- HGNC ID
- HGNC:15749
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